AJIC: American Journal of Infection Control
Volume 35, Issue 10 , Pages 631-637 , December 2007

National prevalence of methicillin-resistant Staphylococcus aureus in inpatients at US health care facilities, 2006

  • William R. Jarvis, MD

      Affiliations

    • Jason and Jarvis Associates, Hilton Head Island, SC
    • Corresponding Author InformationAddress correspondence to William R. Jarvis, MD, 135 Dune Lane, Hilton Head Island, SC 29928.
  • ,
  • JoAnn Schlosser, MA

      Affiliations

    • Association for Professionals in Infection Control and Epidemiology, Inc., Washington, DC
  • ,
  • Raymond Y. Chinn, MD

      Affiliations

    • Sharp Memorial Hospital, San Diego, CA
  • ,
  • Samantha Tweeten, MPH, PhD

      Affiliations

    • County of San Diego Health and Human Services Agency, San Diego, CA
  • ,
  • Marguerite Jackson, PhD, RN

      Affiliations

    • University of California San Diego School of Medicine, San Diego, CA

References 

  1. Haley RW, Hightower AW, Khabbaz RF, Thornsberry C, Martone WJ, Allen JR, et al. The emergence of methicillin-resistant Staphylococcus aureus infections in United States hospitals: possible role of the house staff-patient transfer circuit. Ann Intern Med. 1982;97:297–308
  2. Boyce JM, Causey WA. Increasing occurrence of methicillin-resistant Staphylococcus aureus in the United States. Infect Control. 1982;3:377–383
  3. Kuehnert MJ, Hill HA, Kupronis BA, Tokars JI, Solomon SL, Jernigan DB. Methicillin-resistant-Staphylococcus aureus hospitalizations, United States. Emerg Infect Dis. 2005;11:868–872
  4. Klevens RM, Edwards JR, Tenover FC, McDonald LC, Horan T, Gaynes R. National Nosocomial Infections Surveillance System. Changes in the epidemiology of methicillin-resistant Staphylococcus aureus in intensive care units in US hospitals, 1992-2003. Clin Infect Dis. 2006;43:387–388
  5. American Hospital Association . AHA Hospital Statistics 2005. Chicago, IL: AHA; 2007;
  6. Simonds DN, Jarvis WR, Horan TC, Kelly R, Jarvis WR. Detecting pediatric nosocomial infections: how do infection control and quality assurance personnel compare?. Am J Infect Control. 1997;25:202–208
  7. Sherman ER, Heydon KH, St. John KH, Texner E, Rettig SL, Alexander SK, et al. Administrative data fail to accurately identify cases of healthcare-associated infection. Infect Control Hosp Epidemiol. 2006;27:332–337
  8. Wright SB, Huskins WC, Dokholyan RS, Goldmann DA, Platt R. Administrative databases provide inaccurate data for surveillance of long-term central venous catheter-associated infections. Infect Control Hosp Epidemiol. 2003;24:946–949
  9. Moran CA, Hadler JL. Population-based incidence and characteristics of community-onset Staphylococcus aureus infections with bacteremia in 4 metropolitan Connecticut areas, 1998. J Infect Dis. 2001;184:1029–1034
  10. Rosario-Rosado RV, Rene AA, Jones B. Descriptive analysis of patients with community-onset and hospital-onset methicillin-resistant Staphylococcus aureus infections. Infect Control Hosp Epidemiol. 2004;25:171–173
  11. King MD, Humphrey BJ, Wang YF, Kourbarova EV, Ray SM, Blumberg HM. Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections. Ann Intern Med. 2006;144:309–317
  12. File TM. Impact of community-acquired methicillin-resistant Staphylococcus aureus in the hospital setting. Cleve Clin J Med. 2007;74(Suppl 4):S6–S11
  13. Furuya EY, Cook HA, Lee MH, Miller M, Larson E, Hyman S, et al. Community-associated methicillin-resistant Staphylococcus aureus prevalence: how common is it? A methodological comparison of prevalence ascertainment. Am J Infect Control. 2007;35:359–366
  14. Popovich K, Hota B, Rice T, Aroutcheva A, Weinstein RA. Phenotypic prediction rule for community-associated methicillin-resistant Staphylococcus aureus. J Clin Microbiol. 2007;45:2293–2295
  15. Tsuji BT, Rybak MJ, Cheung CM, Amjad M, Kaatz GW. Community- and health care-associated methicillin-resistant Staphylococcus aureus: a comparison of molecular epidemiology and antimicrobial activities of various agents. Diagn Microbiol Infect Dis. 2007;58:41–47
  16. Skiest DJ, Brown K, Cooper TW, Hoffman-Roberts H, Mussa HR, Elliott AC. Prospective comparison of methicillin-susceptible and methicillin-resistant community-associated Staphylococcus aureus infections in hospitalized patients. J Infect. 2007;54:427–434
  17. Huang H, Flynn NM, King JH, Monchaud C, Morita M, Cohen SH. Comparisons of community-associated methicillin-resistant Staphylococcus aureus (MRSA) and hospital-associated MSRA infections in Sacramento, California. J Clin Microbiol. 2006;44:2423–2427
  18. Frank AL, Marcinak JF, Mangat PD, Schreckenberger PC. Community-acquired and clindamycin-susceptible methicillin-resistant Staphylococcus aureus in children. Pediatr Infect Dis J. 1999;18:993–1000
  19. Herold BC, Immergluck LC, Maranan MC, Lauderdale DS, Gaskin RE, Boyle-Vavra S, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA. 1998;279:593–598
  20. Gorak EJ, Yamada SM, Brown JD. Community-acquired methicillin-resistant Staphylococcus aureus in hospitalized adults and children without known risk factors. Clin Infect Dis. 1999;29:797–800
  21. Sattler CA, Mason EO, Kaplan SL. Prospective comparison of risk factors and demographic and clinical characteristics of community-acquired, methicillin-resistant versus methicillin-susceptible Staphylococcus aureus infection in children. Pediatr Infect Dis J. 2002;21:910–917
  22. Martinez-Aquilar G, Hammerman WA, Mason EO, Kaplan SL. Clindamycin treatment of invasive infections caused by community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus in children. Pediatr Infect Dis J. 2003;22:593–598
  23. Salgado CD, Farr BM. What proportion of hospital patients colonized with methicillin-resistant Staphylococcus aureus are identified by clinical microbiological cultures?. Infect Control Hosp Epidemiol. 2006;27:116–121
  24. Muto CA, Jernigan JA, Ostrowsky BE, Richet HM, Jarvis WR, Boyce JM, et al. SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus. Infect Control Hosp Epidemiol. 2003;24:362–386
  25. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control. 1988;16:128–140
  26. Salgado CD, Farr BM, Calfee DP. Community-acquired methicillin-resistant Staphylococcus aureus: a meta-analysis of prevalence and risk factors. Clin Infect Dis. 2003;36:131–139
  27. Friedman ND, Kaye KS, Stout JE, McGarry SA, Trivette SL, Briggs JP, et al. Health-care-associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med. 2002;137:791–797
  28. Lesens O, Hansmann Y, Brannigan E, Hopkins S, Meyer P, O'Connel B, et al. Healthcare-associated Staphylococcus aureus bacteremia and the risk for methicillin resistance: is the Centers for Disease Control and Prevention definition for community-acquired bacteremia still appropriate?. Infect Control Hosp Epidemiol. 2005;26:204–209
  29. Layton MC, Hierholzer WJ, Patterson JE. The evolving epidemiology of methicillin-resistant Staphylococcus aureus at a university hospital. Infect Control Hosp Epidemiol. 1995;16:12–17
  30. Seigel JD, Rhinehart E, Jackson M, Chiarello L, and the Healthcare Infection Control Practices Advisory Committee. Management of multidrug-resistant organisms in healthcare settings, 2006. Available at: http://www.cdc.gov/ncidod/dhqp/index.html. Accessed November 2007.
  31. Seigel JD, Rhinehart E, Jackson M, Chiarello L, and the Healthcare Infection Control Practices Advisory Committee. 2007 Guideline for isolation precautions: preventing transmission of infectious agents in healthcare settings. Available at: http://www.cdc.gov/ncidod/dhqp/gl.isolation.html. Accessed November 2007.
  32. Association for Professionals in Infection Control and Epidemiology, Inc. Guide to the elimination of methicillin-resistant Staphylococcus aureus (MRSA) transmission in hospital settings. APIC, Washington, DC. MRSA implementation guide. Available at: http://www.apic.org/Content/NavigationMenu/GovernmentAdvocacy/MethicillinResistantStaphylococcusAureusMRSA/Resources/MRSAguide.pdf. Accessed November 2007.
  33. Salgado CD, Farr BM. The importance of infection control in controlling antimicrobial resistant pathogens. In:  Jarvis WR editors. Hospital infections. Philadephia: Wolters Kluwer/Lippincott Williams and Wilkins; 2007;p. 673–688

 Reprints are not available.

 Supported by the APIC Scientific Research Council (previously the Research Foundation) and the APIC.

 This study was presented at the 2007 Annual APIC meeting, San Jose, CA.

PII: S0196-6553(07)00772-9

doi: 10.1016/j.ajic.2007.10.009

AJIC: American Journal of Infection Control
Volume 35, Issue 10 , Pages 631-637 , December 2007