AJIC: American Journal of Infection Control
Volume 38, Issue 4 , Pages 259-263 , May 2010

Management of a multidrug-resistant Acinetobacter baumannii outbreak in an intensive care unit using novel environmental disinfection: A 38-month report

  • Carlo La Forgia, MD

      Affiliations

    • Department of Medicine, University of Chicago, Evanston, IL
    • Department of Medicine, NorthShore University HealthSystem, Evanston, IL
    • ,
  • John Franke, PhD

      Affiliations

    • Department of Environmental Services, NorthShore University HealthSystem, Evanston, IL
    • ,
  • Donna M. Hacek, MT (ASCP)

      Affiliations

    • Department of Pathology and Laboratory Medicine, Division of Microbiology, NorthShore University HealthSystem, Evanston, IL
    • ,
  • Richard B. Thomson Jr., PhD

      Affiliations

    • Department of Pathology and Laboratory Medicine, Division of Microbiology, NorthShore University HealthSystem, Evanston, IL
    • Department of Laboratory Medicine and Pathology, University of Chicago, Evanston, IL
    • ,
  • Ari Robicsek, MD

      Affiliations

    • Department of Medicine, University of Chicago, Evanston, IL
    • Division of Infectious Diseases, NorthShore University HealthSystem, Evanston, IL
    • ,
  • Lance R. Peterson, MD

      Affiliations

    • Department of Medicine, University of Chicago, Evanston, IL
    • Department of Pathology and Laboratory Medicine, Division of Microbiology, NorthShore University HealthSystem, Evanston, IL
    • Department of Laboratory Medicine and Pathology, University of Chicago, Evanston, IL
    • Division of Infectious Diseases, NorthShore University HealthSystem, Evanston, IL
    • Corresponding Author InformationAddress correspondence to Lance R. Peterson, MD, NorthShore University HealthSystem, Department of Pathology and Laboratory Medicine, 2650 Ridge Ave, Evanston, IL 60201.

References 

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  2. Munoz-Price LS, Weinstein RA. Acinetobacter infection. N Engl J Med. 2008;358:1271–1281
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  4. Hota S, Hirji Z, Stockton K, Lemieux C, Dedier H, Wolfaardt G, et al. Outbreak of multidrug-resistant Pseudomonas aeruginosa colonization and infection secondary to imperfect intensive care unit room design. Infect Control Hosp Epidemiol. 2009;30:25–33
  5. Bergogne-Bérézin E, Towner KJ. Acinetobacter spp as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin Microbiol Rev. 1996;9:148–165
  6. Podnos YD, Cinat ME, Wilson SE, Cooke J, Gornick W, Thrupp LD. Eradication of multidrug-resistant Acinetobacter from an intensive care unit. Surg Infect. 2001;2:297–301
  7. Pimentel JD, Low J, Styles K, Harris OC, Hughes A, Athan E. Control of an outbreak of multidrug-resistant Acinetobacter baumannii in an intensive care unit and a surgical ward. J Hosp Infect. 2005;59:249–253
  8. Corbella X, Montero A, Pujol M, Domínguez MA, Ayats J, Argerich MJ, et al. Emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multiresistant Acinetobacter baumannii. J Clin Microbiol. 2000;38:4086–4095
  9. Denton M, Wilcox MH, Parnell P, Green D, Keer V, Hawkey PM, et al. Role of environmental cleaning in controlling an outbreak of Acinetobacter baumannii on a neurosurgical intensive care unit. J Hosp Infect. 2004;56:106–110
  10. Denton M, Wilcox MH, Parnell P, Green D, Keer V, Hawkey PM, et al. Role of environmental cleaning in controlling an outbreak of Acinetobacter baumannii on a neurosurgical intensive care unit. Intensive Crit Care Nurs. 2005;21:94–98
  11. Wilks M, Wilson A, Warwick S, Price E, Kennedy D, Ely A, et al. Control of an outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus colonization and infection in an intensive care unit (ICU) without closing the ICU or placing patients in isolation. Infect Control Hosp Epidemiol. 2006;27:654–658
  12. Chan P-C, Li-Min Huang L-M, Lin H-C, Chany LY, Chen ML, Lu CY, et al. Control of an outbreak of pandrug-resistant Acinetobacter baumannii colonization and infection in a neonatal intensive care unit. Infect Control Hosp Epidemiol. 2007;28:423–429
  13. Enoch DA, Summers C, Brown NM, Moore L, Gillham MI, Burnstein RM, et al. Investigation and management of an outbreak of multidrug-carbapenem-resistant Acinetobacter baumannii in Cambridge, UK. J Hosp Infect. 2008;70:109–118
  14. Apisarnthanarak A, Pinitchai U, Thongphubeth K, Yuekyen C, Warren DK, Fraser VJ for the Thammasat University Pandrug-Resistant Acinetobacter baumannii Control Group. A multifaceted intervention to reduce pandrug-resistant Acinetobacter baumannii colonization and infection in 3 intensive care units in a Thai tertiary care center: a 3-year study. Clin Infect Dis. 2008;47:760–767
  15. Karageorgopoulos DE, Falagas ME. Current control and treatment of multidrug-resistant Acinetobacter baumannii infections. Lancet Infect Dis. 2008;8:751–762
  16. Valencia R, Arroyo LA, Conde M, Aldana JM, Torres MJ, Fernández-Cuenca F, et al. Nosocomial outbreak of infection with pandrug-resistant Acinetobacter baumannii in a tertiary care university hospital. Infect Control Hosp Epidemiol. 2009;30:257–263
  17. Morgan DJ, Weisenberg SA, Augenbraun MH, Calfee DP, Currie BP, Furuya EY, et al. Multidrug-resistant Acinetobacter baumannii in New York City: 10 years into the epidemic. Infect Contr Hosp Epidemiol. 2009;30:196–197

 This project was supported by NorthShore University HealthSystem.

 Conflicts of interest: None to report.

PII: S0196-6553(09)00836-0

doi: 10.1016/j.ajic.2009.07.012

AJIC: American Journal of Infection Control
Volume 38, Issue 4 , Pages 259-263 , May 2010

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