AJIC: American Journal of Infection Control
Volume 38, Issue 3 , Pages 173-181 , April 2010

Exposure to hospital roommates as a risk factor for health care–associated infection

  • Meghan Hamel, MSc

      Affiliations

    • Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada
    • ,
  • Dick Zoutman, MD, FRCPC

      Affiliations

    • Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada
    • Department of Pathology and Molecular Medicine Queen's University, Kingston, Ontario, Canada
    • Corresponding Author InformationAddress correspondence to Dick Zoutman, MD, FRCPC, Infection Prevention and Control Service, Professor of Pathology and Molecular Medicine and of Medicine, Queen's University and University Hospitals Kingston, 76 Stuart St, Kingston, Ontario, Canada K7L 2V7.
    • ,
  • Chris O'Callaghan, DVM, MSc, PhD

      Affiliations

    • Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada

References 

  1. Borg MA. Bed occupancy and overcrowding as determinant factors in the incidence of MRSA infections within general ward settings. J Hosp Infect. 2003;54:316–318
  2. World Health Organization. Hospital-acquired infections. Available from: http://www.euro.who.int/surveillance/cooperation/20050707_1. Accessed October 5, 2005.
  3. Baker GR, Norton PG, Flintoft V, Blais R, Brown A, Cox J, et al. The Canadian Adverse Events Study: the incidence of adverse events among hospital patients in Canada. CMAJ. 2004;170:1678–1686
  4. Centers for Disease Control and Prevention. Campaign to Prevent Antimicrobial Resistance in Healthcare Settings. Available from: http://www.cdc.gov/drugresistance/healthcare/problem.htm. Accessed October 5, 2005.
  5. Zoutman DE, Ford D, Bryce E, Gourdeau M, Hébert G, Henderson E, et al. Canadian Hospital Epidemiology Committee, Canadian Nosocomial Infection Surveillance Program, Health Canada. The state of infection surveillance and control in Canadian acute care hospitals. Am J Infect Control. 2003;31:266–273
  6. Bowbrow M, Thomas J. Inpatient care facilities. In:  Kliment SA editors. Building type basics for healthcare facilities. New York: Wiley; 2000;p. 131–191
  7. Girou E, Stephan F, Novara A, Safar M, Fagon JY. Risk factors and outcome of nosocomial infections: results of a matched case-control study of ICU patients. Am J Respir Crit Care Med. 1998;157:1151–1158
  8. Sax H, Hugonnet S, Harbarth S, Herrault P, Pittet D. Variation in nosocomial infection prevalence according to patient care setting: a hospital-wide survey. J Hosp Infect. 2001;48:27–32
  9. Simor AE, Ofner-Agostini M, Bryce E, Green K, McGeer A, Mulvey M, et al. the Canadian Nosocomial Infection Surveillance Program (Health Canada). The evolution of methicillin-resistant Staphylococcus aureus in Canadian hospitals: 5 years of national surveillance. CMAJ. 2001;165:21–26
  10. Shirani KZ, McManus AT, Vaughan GM, McManus WF, Pruitt BA, Mason AD. Effects of environment of infection in burn patients. Arch Surg. 1986;121:31–36
  11. Coalition for Health Environments Research. The use of single patient rooms versus multiple occupancy rooms in acute care environments. Study commissioned by Facility Guidelines Institute (FGI) to the Coalition for Health Environments Research (CHER) 2003. Available from: http://www.premierinc.com/all/safety/resources/construction/downloads/aia-cher-private-room.doc. Accessed January 11, 2006.
  12. Kibbler CC, Quick A, O'Neill A-M. The effect of increased bed numbers on MRSA transmission in acute medical wards. J Hosp Infect. 1997;39:213–219
  13. O'Connell NH, Humphreys H. Intensive care unit design and enironmental factors in the acquisition of infection. J Hosp Infect. 2000;45:255–262
  14. Ulrich R, Quan X, Zimring C, Joseph A, Choudhary R. The role of the physical environment in the hospital of the 21st century: a once-in-a-lifetime opportunity. Report to The Center for Health Design for the Designing the 21st Century Hospital Project. September 2004;
  15. Archibald LK, Manning ML, Bell LM, Banerjee S, Jarvis WR. Patient density, nurse-to-patient ratio and nosocomial infection risk in a pediatric cardiac intensive care unit. Pediatr Infect Dis J. 1997;16:1045–1048
  16. Chang VT, Nelson K. The role of physical proximity in nosocomial diarrhea. Clin Infect Dis. 2000;31:717–722
  17. Harbarth S, Sudre P, Dharan S, Cadenas M, Pittet D. Outbreak of Enterobacter cloacae related to understaffing, overcorowding, and poor hygiene practices. Infect Control Hosp Epidemiol. 1999;20:598–603
  18. Vicca AF. Nursing staff workload as a determinant of methicillin-resistant Staphylococcus aureus spread in an adult intensive therapy unit. J Hosp Infect. 1999;43:109–113
  19. Austin DJ, Bonten MJM, Weinstein RA, Slaughter S, Anderson RM. Vancomycin-resistant enterococci in intensive-care hospital settings: transmission dynamics, persistance, and the impact of infection control programs. Proc Natl Acad Sci USA. 1999;96:6908–6913
  20. Boyce JM, Potter-Bynoe G, Chenevert C, King T. Environmental contamination due to methicillin-resistant Staphylococcus aureus: possible infection control implications. Infect Control Hosp Epidemiol. 1997;18:622–627
  21. Duckro AN, Blom DW, Lyle EA, Weintein RA, Hayden MK. Transfer of vancomycin-resistant enterococci via health care worker hands. Arch Intern Med. 2005;165:302–307
  22. McBryde ES, Bradley LC, Whitby M, McElwain DLS. An investigation of contact transmission of methicillin-resistant Staphylococcus aureus. J Hosp Infect. 2004;58:104–108
  23. UK Department of Health. A simple guide to Clostridium difficile. Available from: www.dh.gov.uk/hcai. Accessed January 11, 2006.
  24. Chotani RA, Roghmann M-C, Perl TM. Nosocomial infections. In:  Nelson KE,  Williams CM,  Graham NMH editor. Infectious disease epidemiology: theory and Practice. Gaithersburg, MD: Aspen; 2001;p. 357–407
  25. In:  Tierney LM,  McPhee SJ,  Papadakis MA editor. Current medical diagnosis and treatment. 44th ed. New York: Lange; 2005;p. 1248–1250
  26. Kyne L, Farrell RJ, Kelly CP. Clostridium difficile. Gastroenterol Clin North Am. 2001;30:753–777
  27. In:  Murray PR,  Baron EJ,  Jorgensen JH,  Landry ML,  Pfaller MA editor. Manual of clinical microbiology. 9th ed. Washington, DC: American Society for Microbiology Press; 2007;
  28. Iowa Department of Public Health. Enterococci (vancomycin-resistant). Available from: http://www.idph.state.ia.us/adper/common/pdf/epi_manual/enterococci.pdf. Accessed April 5 2007.
  29. Iowa Department of Public Health. Staphylococcus aureus (methicillin-resistant). Available from: http://www.idph.state.ia.us/adper/common/pdf/epi_manual/staph.pdf. Accessed April 5, 2007.
  30. Manitoba Health, Public Health. Communicable disease management protocol: methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA/VRSA) infection. Available from: http://www.gov.mb.ca/health/publichealth/cdc/protocol/meth.pdf. Accessed April 5, 2007.
  31. Rothman KJ, Greenland S. Modern epidemiology. Philadelphia: Lippincott-Raven; 1999;
  32. Bacon AS. Efficient hospitals. JAMA. 1920;72:123–126
  33. Bracco D, Dubois M-J, Bouali R, Eggimann P. Single rooms may help to prevent nosocomial bloodstream infection and cross-transmission of methicillin-resistant Staphylococcus aureus in intensive care units. Intens Care Med. 2007;33:836–840
  34. Torniporth NG, Roberts RB, John J, Hafner A, Riley LW. Risk factors associated with vancomycin-resistant Entercoccus faecium infection or colonization in 145 matched case patients and control patients. Clin Infect Dis. 1996;23:767–772
  35. Byers KE, Anglim AM, Anneski CJ, Germanson TP, Gold HS, Durbin LJ, et al. A hospital epidemic of vancomycin-resistant enterococcus: risk factors and control. Infect Control Hosp Epidemiol. 2001;22:140–147
  36. McFarland LV, Mulligan ME, Kwok RYY, Stamm WE. Nosocomial acquisition of Clostridium difficile infection. N Engl J Med. 1989;320:204–210
  37. Moore C, Dhaliwal J, Tong A, Eden S, Wigston C, Willey B, et al. Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) acquisition in roommate contacts of patients colonized or infected with MRSA in an acute-care hospital. Infect Control Hosp Epidemiol. 2008;29:600–606
  38. Cepeda JA, Whitehouse T, Cooper B, Hails J, Jones K, Kwaku F, et al. Isolation of patients in single rooms or cohorts to reduce spread of MRSA in intensive-care units: prospective two-centre study. Lancet. 2005;365:295–304
  39. Huycke MM, Sahm DF, Gilmore MS. Multiple-drug resistant enterococci: the nature of the problem and an agenda for the future. Emerg Infect Dis. 1998;4:239–249
  40. Loeb M, Salama S, Armstrong-Evans M, Capretta G, Olde J. A case-control study to detect modifiable risk factors for colonization with vancomycin-resistant enterococci. Infect Control Hosp Epidemiol. 1999;20:760–763
  41. Canadian Institute for Health Information. Resource intensity weights and expected length of stay. Available from: http://secure.cihi.ca/cihiweb/dispPage.jsp?cw_page = casemix_riw_e. Accessed June 11, 2006.
  42. Berry LL, Parker D, Coile RC, Hamilton DK, O'Neill DD, Sadler BL. The business case for better buildings. Frontiers Health Serv Manag. 2004;21:3–24
  43. Ulrich RS, Zimring C, Quan X, Joseph A. The role of the physical environment in the hospital of the 21st century. Report sponsored by the Robert Wood Johnson Foundation and the Center for Health Design, 2004. Available from: www.rwjf.org and www.healthdesign.org. Accessed August 8, 2009.
  44. Marberry S, editor. Improving healthcare with better building design. Chicago: Health Administration Press; 2006. Available from: www.healthdesign.org/research/reports. Accessed August 8, 2009.

PII: S0196-6553(09)00898-0

doi: 10.1016/j.ajic.2009.08.016

AJIC: American Journal of Infection Control
Volume 38, Issue 3 , Pages 173-181 , April 2010

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