| | Research findings from nonpharmaceutical intervention studies for pandemic influenza and current gaps in the research published online 15 March 2010. In June 2006, the Centers for Disease Control and Prevention released a request for applications to identify, improve, and evaluate the effectiveness of nonpharmaceutical interventions (NPIs)—strategies other than vaccines and antiviral medications—to mitigate the spread of pandemic influenza within communities and across international borders (RFA-CI06-010). These studies have provided major contributions to seasonal and pandemic influenza knowledge. Nonetheless, key concerns were identified related to the acceptability and protective efficacy of NPIs. Large-scale intervention studies conducted over multiple influenza epidemics, as well as smaller studies in controlled laboratory settings, are needed to address the gaps in the research on transmission and mitigation of influenza in the community setting. The current novel influenza A (H1N1) pandemic underscores the importance of influenza research. a Center for Social Epidemiology and Population Health, Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI b Center for Infectious Diseases & Emergency Readiness, Division of Epidemiology, School of Public Health, University of California, Berkeley, CA c Pandemic Influenza Research Group, University of Otago, New Zealand d Public Health and Social Policy Division, RTI International, Research Triangle Park, NC e Department of Community Medicine and School of Public Health, University of Hong Kong, Hong Kong, People's Republic of China f Work Environment Department, School of Health & Environment, University of Massachusetts, Lowell, MA g Department of Environmental Health, School of Public Health, Harvard University, Boston, MA h School of Nursing, Mailman School of Public Health, Columbia University, New York, NY i Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY j Center for History of Medicine, University of Michigan Medical School, Ann Arbor, MI k Maryland Institute for Applied Environmental Health, Department of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park, MD l Disease Outbreak Control Division, Hawaii Department of Health, Honolulu, HI m Center for Public Health Preparedness, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA  Address correspondence to Allison E. Aiello, PhD, MS, Center for Social Epidemiology and Population Health, 1415 Washington Heights, Ann Arbor, MI 48109.
Charles J. Vukotich, Jr, MS, Center for Public Health Practice, Graduate School of Public Health, University of Pittsburgh, A711 Crabtree, 130 DeSoto St, Pittsburgh PA 15261. Conflicts of interest: None to report. PII: S0196-6553(10)00039-8 doi:10.1016/j.ajic.2009.12.007 © 2010 Association for Professionals in Infection Control and Epidemiology, Inc. All rights reserved. | |
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