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Abstract
Body substance isolation (BSI) is a system of infection precautions intended to reduce
nosocomial transmission of infectious agents among patients and to reduce the risk
of transmission of hepatitis B virus, human immunodeficiency virus, and other infectious
agents to health care personnel. Harborview Medical Center in Seattle, Wash, was the
first facility in the United States to implement the BSI system. Between 1984 and
1988 a systematic evaluation of the implementation process was conducted and the effects
of BSI on appropriate glove use by hospital personnel and on the incidence of nosocomial
colonization and infection by sentinel organisms was measured. Results of the evaluation
showed (1) significant increments in knowledge of infection control procedures and
practices as measured by comparing written examination responses before and after
training sessions, (2 significant increases in appropriate glove use as determined
by direct observation of hospital employees for 18 months, and (3) significant reductions
in nosocomial colonization and infection caused by sentinel microorganisms during
the period from 1984 to 1988.
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© 1990 Published by Elsevier Inc.