Abstract
Background: Although many catheter-related bloodstream infections (CR-BSIs) are preventable,
measures to reduce these infections are not uniformly implemented. Objective: To update an existing evidenced-based guideline that promotes strategies to prevent
CR-BSIs. Data Sources: The MEDLINE database, conference proceedings, and bibliographies of review articles
and book chapters were searched for relevant articles. Studies Included: Laboratory-based studies, controlled clinical trials, prospective interventional
trials, and epidemiological investigations. Outcome Measures: Reduction in CR-BSI, catheter colonization, or catheter-related infection. Synthesis: The recommended preventive strategies with the strongest supportive evidence are
education and training of healthcare providers who insert and maintain catheters;
maximal sterile barrier precautions during central venous catheter insertion; use
of a 2% chlorhexidine preparation for skin antisepsis; no routine replacement of central
venous catheters for prevention of infection; and use of antiseptic/antibiotic impregnated
short-term central venous catheters if the rate of infection is high despite adherence
to other strategies (i.e. education and training, maximal sterile barrier precautions
and 2% chlorhexidine for skin antisepsis). Conclusion: Successful implementation of these evidence-based interventions can reduce the risk
for serious catheter-related infection. (Am J Infect Control 2002;30:476-89.)
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Article Info
Footnotes
**See list at end of article.
**This article is being published simultaneously in American Journal of Infection Control and Infection Control and Hospital Epidemiology. The full text of the Guidelines for the Prevention of Intravascular Catheter-Related Infections was published in the Morbidity and Mortality Weekly Report 2002; 51 (No. RR-10) and can be accessed at www.cdc.gov/ncidod/hip/default.htm.
Identification
Copyright
© 2002 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
