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A Comparison of Antimicrobial Efficacy of Alcohol Based Hand Rubs: Impact of Product Format and Active Concentration

      The use and acceptance of alcohol-based hand antiseptics has increased dramatically over the past decade. These products are available in several physical forms, (liquid, gel, foam) with alcohol foams and gels being particularly popular in North America. The question has been raised as to whether the physical format has an inherent impact on product efficacy. The objective of this study was to evaluate the relative antimicrobial performance on human skin of alcohol hand rubs of either (a) the same physical form and same active content, (b) different physical forms with the same active content or (c) the same physical form with different active content. Comparisons: (1) two foam format alcohol based hand rubs (F1 and F2) with active content 62wt% /70%v/v ethyl alcohol (2) two foam format alcohol based hand rubs (F1 & F2) and one gel format alcohol based hand rub (G1) with the same active content of 62wt% /70%v/v ethyl alcohol (3) a gel format alcohol based hand rub (G1) with active content 62wt% /70%v/v ethyl alcohol and a gel format alcohol-based hand rub (G2) with higher active content of 70wt% /77%v/v ethyl alcohol)
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