Evaluation of two organosilane products for sustained antimicrobial activity on high-touch surfaces in patient rooms

Published:January 09, 2014DOI:
      A controlled trial of applying 2 organosilane-based products with antimicrobial properties to high-touch surfaces was conducted in 9 patient rooms. Cultures of surfaces obtained before daily cleaning with a quaternary ammonium disinfectant showed no significant residual antimicrobial activity of the organosilane products, although a modest reduction could not be excluded.

      Key Words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to American Journal of Infection Control
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


      1. Rutala WA, Weber DJ, and and the Healthcare Infection Control Practices Advisory Committee. Guideline for disinfection and sterilization in healthcare facilities, 2008. Available from: Accessed September 29, 2012.

        • Boyce J.M.
        • Havill N.L.
        • Dumigan D.G.
        • Golebiewski M.
        • Balogun O.
        • Rizvani R.
        Monitoring the effectiveness of hospital cleaning practices using ATP bioluminescence assay.
        Infect Control Hosp Epidemiol. 2009; 30: 678-684
        • Carling P.C.
        • Briggs J.L.
        • Perkins J.
        • Highlander D.
        Improved cleaning of patient rooms using a new targeting method.
        Clin Infect Dis. 2006; 42: 385-388
        • Hayden M.K.
        • Bonten M.J.
        • Blom D.W.
        • Lyle E.A.
        • van de Vijver D.A.
        • Weinstein R.A.
        Reduction in acquisition of vancomycin-resistant enterococcus after enforcement of routine environmental cleaning measures.
        Clin Infect Dis. 2006; 42: 1552-1560
        • Baxa D.
        • Shetron-Rama L.
        • Golembieski M.
        • Golembieski M.
        • Jain S.
        • Gordon M.
        • et al.
        In vitro evaluation of a novel process for reducing bacterial contamination of environmental surfaces.
        Am J Infect Control. 2011; 39: 483-487
        • Huslage K.
        • Rutala W.A.
        • Sickbert-Bennett E.
        • Weber D.J.
        A quantitative approach to defining “high-touch” surfaces in hospitals.
        Infect Control Hosp Epidemiol. 2010; 31: 850-853
        • Kundrapu S.
        • Sunkesula V.
        • Jury L.A.
        • Sitzlar B.M.
        • Donskey C.J.
        Daily disinfection of high-touch surfaces in isolation rooms to reduce contamination of healthcare workers’ hands.
        Infect Control Hosp Epidemiol. 2012; 33: 1039-1042
        • Rutala W.A.
        • Gergen M.F.
        • Weber D.J.
        Microbiologic evaluation of microfiber mops for surface.
        Am J Infect Control. 2012; 35: 569-573
        • Boyce J.M.
        • Havill N.L.
        Evaluation of a new hydrogen peroxide wipe disinfectant.
        Infect Control Hosp Epidemiol. 2012; 34: 521-523