Outcomes of a ventilator-associated pneumonia bundle on rates of ventilator-associated pneumonia and other health care-associated infections in a long-term acute care hospital setting

      Long-term trends in ventilator-associated pneumonia (VAP) rates, and other health care-associated infections, were examined prior to, during, and after introduction of a VAP bundle in a long-term acute care hospital setting. VAP incidence rate declined in a step-wise fashion and reached a null value. Incidence rates of bacteremia from any cause declined in a similar fashion. The incidence rates of vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus colonization or infection rates also decreased, but that of Clostridium difficile infection did not. VAP in the long-term acute care hospital setting can be controlled over time with implementation of Centers for Disease Control and Prevention-based VAP bundle. This outcome also may decrease certain other health care-associated infections.

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        • Buczko W.
        Ventilator-associate pneumonia among elderly Medicare beneficiaries in long-term care hospitals.
        Health Care Financing Rev. 2009; 1: 1-10
        • Walkey A.J.
        • Campbell-Reardon C.
        • Sulis C.A.
        • Nace R.N.
        • Joyce-Brady M.
        Epidemiology of ventilator-associated pneumonia in a long-term acute care hospital.
        Infect Control Hosp Epidemiol. 2009; 30: 319-324
        • Korah J.M.
        • Rumbach M.J.
        • Cancio M.R.
        • Solomon D.A.
        Significant reduction of ventilator-associated pneumonia rates associated with the introduction of a prevention protocol and maintained for 10 years.
        ICU Director. 2010; 1: 137
      1. Buczko W. Ventilator-associated pneumonia among the elderly in long-term hospitals: 2005-2010. Presented as Abstract 262818 at the Program and Abstracts of the 140th Annual Meeting of the American Public Health Association (APHA); 2012; San Francisco, CA.

        • Munoz-Price L.S.
        Long-term acute care hospitals.
        Clin Infect Dis. 2009; 49: 438-443
        • Thomas B.W.
        • Maxwell R.A.
        • Dart B.W.
        • Hartmann E.H.
        • Bates D.L.
        • Mejia V.A.
        • et al.
        Errors in administrative-reported ventilator-associated pneumonia rates: are never events really so?.
        Am Surg. 2011; 77: 998-1002
        • Huzar T.F.
        • Cross J.M.
        Ventilator-associated pneumonia in burn patients: a cause or consequence of critical illness?.
        Expert Rev Respir Med. 2011; 5: 663-673
        • Klompas M.
        Complications of mechanical ventilation—the CDC's new surveillance program.
        N Engl J Med. 2013; 368: 1472-1475