From 2009-2012, a total of 281 episodes of central line–associated candidemia were identified, and the overall incidence was 2.05 episodes per 1,000 hospital admissions. More than half of the patients were classified as older adults, with an age ≥65 years. Cancer was the most common underlying disease (n = 231, 82.2%). Twenty patients had polycandidal candidemia, and 94 had concomitant bacteremia. The overall in-hospital mortality rate was 50.9%, and a multivariable analysis showed that this rate was only significantly associated with a Charlson comorbidity index score >5, jaundice, no antifungal agent use, and use of mechanical ventilators.
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Published online: September 17, 2014
Conflicts of interest: None to report.
Author contributions: Draft preparation: Tang. Data analysis: Liu and Lin. Data acquisition: Lai. Critical review and approval of final version: Lai.
© 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.