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Letters to the Editor| Volume 42, ISSUE 11, P1250-1253, November 2014

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Response to commentary on “Assessing risk of health care–acquired Legionnaires' disease from environmental sampling: The limits of using a strict percent positivity approach”

      We appreciate the commentary from Pierre et al
      • Pierre D.
      • Stout J.E.
      • Yu V.L.
      Editorial commentary: risk assessment and prediction for health care–associated Legionnaires' disease: percent distal site positivity as a cut-point.
      regarding our article published in the American Journal of Infection Control in 2012.
      • Allen J.G.
      • Myatt T.A.
      • Macintosh D.L.
      • Ludwig J.F.
      • Minegishi T.
      • Stewart J.H.
      • et al.
      Assessing risk of health care-acquired Legionnaires’ disease from environmental sampling: the limits of using a strict percent positivity approach.
      One of our goals was to start a discourse on the utilization of 30% prevalence of Legionella in a hospital water system as a reliable decision point for determining the risk of Legionnaires' disease and subsequent interventions, and we welcome the opportunity to discuss this important issue further. As shown in our article, and will be further demonstrated in this response, this 30% cut-off has been adopted and referenced by various government agencies and peer-reviewed journal articles without critical evaluation since its emergence in 1983. Given its ambiguous evolution and the significance that has been apportioned to it, it was necessary and prudent to evaluate the validity of this metric. Our study was the first and only systematic effort to do so.
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