Background
Reported rates of neonatal health care–associated infections (HAIs) in neonatal intensive
care units (NICUs) have risen rapidly in recent years. Little data are available in
Egypt, however. The aim of the present study was to determine the incidence of and
risk factors for HAIs in the NICU of Ain Shams University Hospital of Obstetrics and
Gynecology.
Methods
A prospective study was carried out on all neonates admitted in the NICU of Ain Shams
University Hospital of Obstetrics and Gynecology in 2012. Centers for Disease Control
and Prevention criteria were followed for identifying HAIs.
Results
A total of 434 neonates were enrolled in the study. The cumulative incidence of HAIs
in the NICU was 28%. Bloodstream infections accounted for 85% of HAI episodes; pneumonia,
for 10%. The most common organism isolated was Klebsiella spp. The main risk factors identified on multivariable analysis were gestational
age <38 weeks (relative risk [RR], 1.63), birth weight <1,500 g (RR, 1.39), mechanical
ventilation (RR, 1.74), and surgical procedures (RR, 1.65). The mortality rate attributed
to HAIs was 11.75%, and the extra hospital length of stay attributed to HAIs was 8 days.
Conclusion
The high incidence of HAI identified in the study NICU mandates more vigorous infection
control interventions.
Key Words
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Article info
Publication history
Published online: September 17, 2014
Footnotes
Conflict of interest: None to report.
Identification
Copyright
© 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
