Brief report| Volume 42, ISSUE 11, P1235-1237, November 2014

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Bloodstream infections and inpatient length of stay among pediatric cancer patients with febrile neutropenia in Mexico City

Published:September 15, 2014DOI:
      We assessed the association between bloodstream infections (BSIs) and inpatient length of stay among pediatric cancer patients with febrile neutropenia in Mexico City. The estimated length of stay for BSIs was 19 days, which corresponded with a 100% (95% confidence limits, 60%–160%) relative increase in the length of stay compared with patients for whom no pathogen was identified. Feasible options for reducing the length of stay should be considered to alleviate patient and resource burden.

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        • Meckler G.
        • Lindemulder S.
        Fever and neutropenia in pediatric patients with cancer.
        Emerg Med Clin North Am. 2009; 27: 525-544
        • Hakim H.
        • Flynn P.M.
        • Knapp K.M.
        • Srivastava D.K.
        • Gaur A.H.
        Etiology and clinical course of febrile neutropenia in children with cancer.
        J Pediatr Hematol Oncol. 2009; 31: 623-629
        • Basu S.K.
        • Fernandez I.D.
        • Fisher S.G.
        • Asselin B.L.
        • Lyman G.H.
        Length of stay and mortality associated with febrile neutropenia among children with cancer.
        J Clin Oncol. 2005; 23: 7958-7966
        • Jones P.D.
        • Henry R.L.
        • Stuart J.
        • Francis L.
        Suspected infection in children with cancer.
        J Qual Clin Pract. 1998; 18: 275-284
        • Biwersi C.
        • Hepping N.
        • Bode U.
        • Fleischhack G.
        • von Renesse A.
        • Exner M.
        • et al.
        Bloodstream infections in a German paediatric oncology unit: prolongation of inpatient treatment and additional costs.
        Int J Hyg Environ Health. 2009; 212: 541-546
        • Magrath I.
        • Steliarova-Foucher E.
        • Epelman S.
        • Ribeiro R.C.
        • Harif M.
        • Li C.K.
        • et al.
        Paediatric cancer in low-income and middle-income countries.
        Lancet Oncol. 2013; 14: e104-e116
        • Horan T.C.
        • Andrus M.
        • Dudeck M.A.
        CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting.
        Am J Infect Control. 2008; 36: 309-332
        • Gutierrez R.G.
        Parametric frailty and shared frailty survival models.
        Stata J. 2002; 2: 22-44
        • Schisterman E.F.
        • Cole S.R.
        • Platt R.W.
        Overadjustment bias and unnecessary adjustment in epidemiologic studies.
        Epidemiology. 2009; 20: 488-495
        • Israels T.
        • Renner L.
        • Hendricks M.
        • Hesseling P.
        • Howard S.
        • Molyneux E.
        SIOP PODC: recommendations for supportive care of children with cancer in a low-income setting.
        Pediatr Blood Cancer. 2013; 60: 899-904
        • Kirn T.J.
        • Weinstein M.P.
        Update on blood cultures: how to obtain, process, report, and interpret.
        Clin Microbiol Infect. 2013; 19: 513-520
        • Haeusler G.M.
        • Mechinaud F.
        • Daley A.J.
        • Starr M.
        • Shann F.
        • Connell T.G.
        • et al.
        Antibiotic-resistant Gram-negative bacteremia in pediatric oncology patients–risk factors and outcomes.
        Pediatr Infect Dis J. 2013; 32: 723-726
        • Pogue J.M.
        • Mynatt R.P.
        • Marchaim D.
        • Zhao J.J.
        • Barr V.O.
        • Moshos J.
        • et al.
        Automated alerts coupled with antimicrobial stewardship intervention lead to decreases in length of stay in patients with gram-negative bacteremia.
        Infect Control Hosp Epidemiol. 2014; 35: 132-138