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Letters to the Editor| Volume 42, ISSUE 11, P1247-1248, November 2014

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Candida krusei fungemia in 7 neonates: Clonality tracked to an infusate

DOI:https://doi.org/10.1016/j.ajic.2014.07.033
Candida krusei fungemia in 7 neonates: Clonality tracked to an infusate
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      Fungemia is considered a major cause of neonatal morbidity and mortality. Candida krusei is an infrequent isolate among healthy hosts, but is a pathogen of concern among immunocompromised patients, in whom it can cause fungemia, endopthalmitis, arthritis, and endocarditis.
      • García-Rodas R.
      • González-Camacho F.
      • Rodríguez-Tudela J.L.
      • Cuenca-Estrella M.
      • Zaragoza O.
      The interaction between Candida krusei and murine macrophages results in multiple outcomes including intracellular survival and escape from killing.
      Infect Immun. 2011; 79: 2136-2144
      It is difficult to treat owing to intrinsic fluconazole resistance and variable susceptibility to flucytosine and amphotericin B.
      • DiazGranados C.A.
      • Martinez A.
      • Deaza C.
      • Valderrama S.
      An outbreak of Candida spp bloodstream infection in a tertiary care centre in Bogotá, Colombia.
      Braz J Infect Dis. 2008; 12: 390-394
      We report an outbreak of C krusei fungemia in the neonatal Intensive care unit (ICU) of our hospital over a short period of 2 weeks.
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      References

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        • González-Camacho F.
        • Rodríguez-Tudela J.L.
        • Cuenca-Estrella M.
        • Zaragoza O.
        The interaction between Candida krusei and murine macrophages results in multiple outcomes including intracellular survival and escape from killing.
        Infect Immun. 2011; 79: 2136-2144
        View in Article
        • DiazGranados C.A.
        • Martinez A.
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        An outbreak of Candida spp bloodstream infection in a tertiary care centre in Bogotá, Colombia.
        Braz J Infect Dis. 2008; 12: 390-394
        View in Article
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      Article info

      Footnotes

      Conflict of interest: None to report.

      Identification

      DOI: https://doi.org/10.1016/j.ajic.2014.07.033

      Copyright

      © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

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