Institution of appropriate airborne infection isolation (AII) precautions for patients
with suspected Mycobacterium tuberculosis is critical to prevent disease transmission. We compared the yield of acid-fast bacilli
smears from different types of respiratory specimens and found that smear sensitivity
was highest for specimens obtained by endotracheal aspirates (92%), followed by sputum
(79%), and then by bronchoalveolar lavage (37%). As a result of this study, our institutional
policy regarding discontinuation of AII precautions was amended.
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References
Centers for Disease Control. A global perspective on Tuberculosis 2011. Available from http://www.cdc.gov/tb/statistics/default.htm. Accessed September 11, 2014.
- Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings, 2005.MMWR Recomm Rep. 2005; 54: 1-141
- Tuberculosis transmission by patients with smear negative pulmonary tuberculosis in a large cohort in the Netherlands.Clin Infect Dis. 2008; 47: 1135-1142
- Comparison of sputum induction with fiberoptic bronchoscopy in the diagnosis of tuberculosis.Am J Respir Crit Care Med. 2000; 162: 2238-2240
- Induced sputum and bronchoscopy in the diagnosis of pulmonary tuberculosis.Thorax. 2002; 57: 1010-1014
- Comparison of sputum induction with broncho-alveolar lavage in the diagnosis of smear-negative pulmonary tuberculosis.Mymensingh Med J. 2008; 17: 115-123
Article info
Publication history
Published online: September 20, 2014
Footnotes
Conflicts of interest: None to report.
Identification
Copyright
© 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.