Highlights
- •Microbial loads on surfaces contribute to health care–acquired infections.
- •Photocatalytic materials destroy organic substances, including microbes.
- •Titanium dioxide is a photocatalytic substance that can be applied as a very safe coating.
- •Infections declined 30% after such a coating was introduced to our facility.
- •Results confirm the logic of the approach and suggest additional studies.
Health care facilities contain potentially contaminated surfaces that are either difficult
to sanitize or prone to recontamination. Photocatalytic materials exhibit antimicrobial
activity when exposed to light and provide a safe, durable coating on a wide range
of surfaces. We assessed infection rates before and after introduction of a photocatalytic
coating in our facility. Infection rates decreased overall by 30%, a change that was
statistically significant (P = .02). Similar changes to the built environment merit additional investigation.
Graphical abstract

Graphical Abstract
Key Words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to American Journal of Infection ControlAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Understanding and preventing transmission of healthcare-associated pathogens due to the contaminated hospital environment.Infect Control Hosp Epidemiol. 2013; 34: 449-452
- Copper surfaces reduce the rate of healthcare-acquired infections in the intensive care unit.Infect Control Hosp Epidemiol. 2013; 34: 479-486
- Broad spectrum microbicidal activity of photocatalysis by TiO2.Catalysts. 2013; 3: 310-323
- Bactericidal activity of photocatalytic TiO2 reaction: toward an understanding of its killing mechanism.Appl Environ Microbiol. 1999; 65: 4094-4098
- Titanium dioxide nanomaterials: synthesis, properties, modifications, and applications.Chem Rev. 2007; 107: 2891-2959
U.S. Centers for Disease Control and Prevention. CDC/NHSN surveillance definitions for specific types of infections. Available from: http://www.cdc.gov/nhsn/pdfs/pscmanual/17pscnosinfdef_current.pdf.
- Does improving surface cleaning and disinfection reduce health care-associated infections?.Am J Infect Control. 2013; 41: S12-S19
Article info
Publication history
Published online: December 16, 2014
Footnotes
Conflicts of interest: None to report.
Identification
Copyright
© 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.