- •We present a pilot randomized controlled trial to evaluate a novel Foley catheter.
- •Novel silver catheter system includes an antimicrobial matrix and antireflux valve.
- •Test system was tolerated and seemingly effective in preventing bacteriuria.
- •Test system seemed especially effective against gram-negative bacilli.
- •A pivotal study is warranted.
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Funding/support: This pilot study was supported by a small business innovation research grant awarded to ICET Inc by the National Institute of Diabetes and Digestive and Kidney Diseases (no. R44 DK55891-06). Leuck is supported by a National Institutes of Health Ruth L. Kirschstein National Research Service Award Institutional Research Training Grant (no. 5T32AI055433-09). This material is also based in part on work supported by the Department of Veterans Affairs (Johnson, no. 1 I01 CX000192 01).
Conflicts of interest: Leuck, Kline, Dhody, Kazempour, and Ferrieri report no conflicts of interest. Johnson reports that he has been a paid independent consultant to ICET (the manufacturer of the test study catheter) and also has received research grants or contracts from Rochester Medical, Merck, Crucell, and Syntiron. Hunt consults on education projects for DePuy Synthes.