Highlights
- •We implemented hydrogen peroxide vapor for terminal room disinfection of select patient rooms.
- •We concurrently documented improvements in hand hygiene compliance.
- •We report a statistically significant reduction in Clostridium difficile infection, vancomycin-resistant enterococci, and extended-spectrum β-lactamase–producing gram-negative bacteria.
- •Our findings suggest that improvement in environmental and hand hygiene reduce multidrug-resistant organism transmission.
We report a statistically significant reduction in Clostridium difficile infection (from 1.38 to 0.90 cases per 1,000 patient days), vancomycin-resistant
enterococci (from 0.21 to 0.01 cases per 1,000 patient days), and extended-spectrum
β-lactamase–producing gram-negative bacteria (from 0.16 to 0.01 cases per 1,000 patient
days) associated with the introduction of hydrogen peroxide vapor for terminal decontamination
of patient rooms and improvements in hand hygiene compliance.
Key Words
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References
- The role played by contaminated surfaces in the transmission of nosocomial pathogens.Infect Control Hosp Epidemiol. 2011; 32: 687-699
- Reduction in acquisition of vancomycin-resistant enterococcus after enforcement of routine environmental cleaning measures.Clin Infect Dis. 2006; 42: 1552-1560
- Preventing the transmission of multidrug-resistant organisms: modeling the relative importance of hand hygiene and environmental cleaning interventions.Infect Control Hosp Epidemiol. 2014; 35: 1156-1162
- Environmental cleaning intervention and risk of acquiring multidrug-resistant organisms from prior room occupants.Arch Intern Med. 2011; 171: 491-494
- Evaluation of hospital room assignment and acquisition of Clostridium difficile infection.Infect Control Hosp Epidemiol. 2011; 32: 201-206
- An evaluation of environmental decontamination with hydrogen peroxide vapor for reducing the risk of patient acquisition of multidrug-resistant organisms.Clin Infect Dis. 2013; 56: 27-35
- Is there a role for “no-touch” automated room disinfection systems in infection prevention and control?.J Hosp Infect. 2013; 83: 1-13
- Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting.Infect Control Hosp Epidemiol. 2008; 29: 723-729
- Implementation of hospital-wide enhanced terminal cleaning of targeted patient rooms and its impact on endemic Clostridium difficile infection rates.Am J Infect Control. 2013; 41: 537-541
- Risk of acquiring extended-spectrum beta-lactamase-producing Klebsiella species and Escherichia coli from prior room occupants in the intensive care unit.Infect Control Hosp Epidemiol. 2013; 34: 453-458
Article info
Footnotes
Conflicts of interest: J.A. Otter is employed part-time by Bioquell. K. Horn has no conflicts to declare.
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© 2015 Published by Elsevier Inc.