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How will the MMR universal mass vaccination change the epidemiologic pattern of mumps? A 2012 Italian serosurvey

      Highlights

      • Evaluation of MMR vaccination on the epidemiological pattern of mumps.
      • A sero-survey was conducted among Apulian blood donors in 2012.
      • 93.4% (95% CI = 92.1-94.5) showed a positive anti-Mumps IgG titre.
      • 10% of people aged 18-26 years (target of vaccination strategy) was susceptible for mumps.
      • Research must be focused on the long time immunogenicity of mumps vaccine.
      To investigate the changes in the epidemiologic pattern of mumps, we carried out a serosurvey among young adults from Apulia, Italy. A convenience sample of 1,764 blood donors were enrolled in 2012: 93.4% (95% confidence interval, 92.1-94.5) showed a positive antimumps immunoglobulin G titre, geometric mean titer was 2.05. Results were consistent with previously published data on the immunogenicity of mumps vaccine but showed a lack of immunity (10% of people aged 18-26 years susceptible for mumps). Future research must be focused on the long-time immunogenicity of the mumps vaccine.

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