- •Staphylococcus aureus bloodstream infections in hospitalized patients are associated with significant mortality.
- •Primary Staphylococcus aureus central line–associated bloodstream infections (CLABSIs) did not differ in their mortality compared with non-CLABSIs.
- •Primary Staphylococcus aureus non–central line–associated bloodstream infections were associated with more bacteremic complications.
- •Infected peripheral intravenous catheters and midlines are the etiology of most non–central line–associated bloodstream infection Staphylococcus aureus bacteremias.
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Conflicts of Interest: None to report.