Highlights
- •Peracetic acid sporicidal wipes were compared with traditional hospital disinfection.
- •Detection rates of indicator organisms with the two methods were similar.
- •HCAI rates with the two methods were not significantly different. However, further long term prospective study is required to confirm this.
- •Peracetic acid wipes were more expensive.
Background
Peracetic acid sporicidal wipes have been shown to be an effective disinfectant, but
in controlled test environments. Their high cost may restrict use.
Aims
This pilot study investigated the efficacy and compared the costs of routine universal
use of peracetic acid sporicidal wipes versus sporicidal quaternary ammonium compound
and alcohol wipes in the disinfection of a hospital environment.
Methods
The routine universal use of peracetic acid wipes (Clinell Sporicidal; GAMA Healthcare
Ltd, London, UK) was allocated to a study ward, whereas the control ward continued
with the use of quaternary ammonium compound wipes (Tuffie 5; Vernacare, Bolton, UK)
and alcohol wipes (PDI Sani-Cloth 70; PDI, Flint, UK). Twenty high-touch areas in
the 2 wards were sampled for the presence of indicator organisms. The weekly detection
rates of indicator organisms and weekly healthcare associated infection (HCAI) rates
in the 2 wards were compared and examined for decreasing trends over the trial period.
Results
The detection rates of indicator organisms and HCAI rates were not significantly different
in the 2 wards, and did not decrease significantly over the trial period. However,
the peracetic acid wipes seem to be more effective against gram-negative organisms
but at a significantly higher cost.
Conclusions
Further prospective studies are needed to assess the cost-effectiveness of peracetic
acid wipes.
Key Words
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References
- The role of the surface environment in healthcare-associated infections.Curr Opin Infect Dis. 2013; 26: 338-344
- Importance of environmental decontamination—a critical view.J Hosp Infect. 2007; 65: 55-57
- Bactericidal properties of peracetic acid and hydrogen peroxide, alone and in combination, and chlorineand formaldehyde against bacterial water strains.Can J Microbiol. 1992; 38: 635-642
- Guideline for disinfection and sterilization in healthcare facilities, 2008.Centers for Disease Control and Prevention, Atlanta (GA)2008 (Available from:) (Accessed August 18, 2015)
- Clinell® sporicidal wipes package insert.GAMA Healthcare Ltd, London, UK2015 (Available from:) (Accessed August 8, 2015)
- Clinical and cost effectiveness of eight disinfection methods for terminal disinfection of hospital isolation rooms contaminated with Clostridium difficile 027.J Hosp Infect. 2012; 82: 114-121
- Efficacy of “sporicidal” wipes against Clostridium difficile.Am J Infect Control. 2011; 39: 212-218
- Tackling C. difficile with environmental cleaning.Nurs Times. 2011; 107: 22-25
- How do we assess hospital cleaning? A proposal for microbiological standards for surface hygiene in hospitals.J Hosp Infect. 2004; 56: 10-15
- Lütticken R. Distribution of multi-resistant Gram-negative versus Gram-positive bacteria in the hospital inanimate environment.J Hosp Infect. 2004; 56: 191-197
- The role of environmental cleaning in the control of hospital-acquired infection.J Hosp Infect. 2009; 73: 378-385
- Controlling multidrug-resistant Gram-negative bacilli in your hospital: a transformational journey.J Hosp Infect. 2015; 89: 254-258
- Financial burden of hospital-acquired Clostridium difficile infection.J Hosp Infect. 1996; 34: 23-30
- Clinical and economic burden of Clostridium difficile infection in Europe: a systematic review of healthcare-facility-acquired infection.J Hosp Infect. 2012; 81: 1-14
Article Info
Publication History
Published online: May 27, 2016
Footnotes
This work was supported by a London School of Hygiene and Tropical Medicine bench fee.
Conflicts of Interest: None to report.
Identification
Copyright
© 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
