BACKGROUND: Traditional methods for determining Clostridium difficile transmission patterns are confounded by an inability to trace interactions among
different settings. Routine use of next-generation sequencing allows preventionists
to identify relationships among C. difficile cases and direct interventions in near real-time. We sought to expand upon our current
knowledge of C. difficile transmission within and surrounding a 270-bed hospital through whole genome sequencing
(WGS).
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