Highlights
- •Two doses of influenza vaccine were administered to the elderly aged 61-102 years.
- •Antibody responses 22 weeks after the vaccination were measured.
- •Seroprotection rates (PRs) against the A(H3N2) and B strains were maintained.
- •The PR against the A(H1N1)pdm09 strain in people aged 61-75 years did not decrease.
This study aimed to examine the effects of a booster vaccination in elderly people
using 2 doses of trivalent inactivated influenza vaccine during the 2012-2013 influenza
epidemic. Seroprotection rates against the A(H1N1)pdm09 strain in younger elderly
people (aged 61-75 years) and the A(H3N2) and B strains in both younger elderly people
(aged 61-75 years) as well as very elderly people (aged 76-102 years) did not decrease
at 22 weeks after vaccination. This approach confers long-lasting antibody responses
and may be useful in clinical practice.
Key Words
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References
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Article info
Publication history
Published online: November 14, 2017
Footnotes
Supported in part by a grant from the Japan Association for Development of Community Medicine, Japan Society for the Promotion of Science KAKENHI (grant No. 15K08846), and the Ministry of Health, Labor and Welfare, Japan (grant No. H26-SHINKOGYOUSEI-SHITEI-003).
Conflicts of interest: None to report.
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Copyright
© 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
