Screening for Clostridium difficile colonization on admission to a hematopoietic stem cell transplant unit may reduce hospital-acquired C difficile infection

Published:November 21, 2017DOI:


      • Screening for C. difficile at a stem cell transplant unit was implemented.
      • Patients positive for C. difficile at admission were placed in contact precaution.
      • Hospital-onset C. difficile infections significantly decreased after instituting screening.
      Clostridium difficile infection rates are higher in patients undergoing hematopoietic stem cell transplants. In our study, patients undergoing hematopoietic stem cell transplants or chemotherapy were screened for C difficile colonization at admission and placed on contact precautions if they were positive. Patient's colonized with C difficile contribute to the overall burden of C difficile infection in hospitals.

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