Highlights
- •The implemented surveillance program helped to control multidrug-resistant organisms.
- •The dissemination of endemic Acinetobacter baumannii was effectively blocked.
- •This study helped to better ascertain the effectiveness of the surveillance program.
Background
The objective of this prospective study was to verify the effectiveness of a multidisciplinary
surveillance program that was implemented in a teaching hospital in southern Brazil,
to prevent and control the spread of multidrug-resistant organisms.
Methods
The program implemented involved establishment of prevention guidelines, hand-hygiene
promotion, isolation of patients colonized or infected by such organisms, enforced
contact precautions, and terminal cleaning and disinfection of isolation rooms. A
microbiology service, previously provided by an external laboratory, was established
in the hospital. Detection of bacteria-resistant genes and molecular typing were performed
also.
Results
Statistically significant differences were observed between the pre- and post-intervention
periods (P = .00198). Control measures were effective in blocking the dissemination of a previously
endemic clone of Acinetobacter baumannii. Changes were observed in the dissemination pattern, from a monoclonal to a polyclonal
mode. The incidence of vancomycin-resistant Enterococcus during the surveillance period was low. Only 2 isolates of BLAKPC-positive Klebsiella pneumoniae (distinct profiles), and 5 isolates of BLASPM-positive Pseudomonas aeruginosa (a single cluster), were detected.
Conclusions
These results indicate that the surveillance program implemented was effective in
preventing the spread of multidrug-resistant organisms in the hospital.
Key Words
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Article info
Publication history
Published online: December 04, 2017
Footnotes
Funding/support: None reported.
Conflicts of interest: None to report.
Author contributions: No one other than the named authors had a role in gathering or preparing the data or writing the article.
Identification
Copyright
© 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
