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The impact of chlorhexidine gluconate on the skin microbiota of children and adults: A pilot study

  • Ashley E. Kates
    Correspondence
    Address correspondence to Ashley E. Kates, PhD, Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, Medical Foundation Centennial Building, 5th Fl, 1685 Highland Ave, Madison, WI 53705.
    Affiliations
    Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, Madison, WI

    Department of Medicine, William S. Middleton Memorial Veterans Hospital, Madison, WI
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  • Michele L. Zimbric
    Affiliations
    Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, Madison, WI

    Department of Medicine, William S. Middleton Memorial Veterans Hospital, Madison, WI
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  • Kaitlin Mitchell
    Affiliations
    Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, Madison, WI
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  • Joseph Skarlupka
    Affiliations
    Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, Madison, WI

    Department of Medicine, William S. Middleton Memorial Veterans Hospital, Madison, WI
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  • Nasia Safdar
    Affiliations
    Division of Infectious Disease, University of Wisconsin School of Medicine & Public Health, Madison, WI

    Department of Medicine, William S. Middleton Memorial Veterans Hospital, Madison, WI
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Published:March 15, 2019DOI:https://doi.org/10.1016/j.ajic.2019.01.024

      Highlights

      • There were no differences in alpha or beta diversity between patients.
      • Adults showed differences in skin microbiome between cases and controls.
      • No changes to the microbiome were seen between groups in children.
      We examined the effect of chlorhexidine gluconate (CHG) bathing on the skin microbiota of adult and pediatric patients. We observed no differences in pediatric patients; however, multiple genera of bacteria were observed to be significantly less abundant in the adults bathing with CHG. Further research is needed to determine the long-term impact of CHG use on the skin microbiota.

      Key Words

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