Highlights
- •15% hand hygiene increase and 1 cleaning yielded similar infection risk reductions.
- •15% hand hygiene increase and 2 cleanings decreased infection risk by 20.93%-47.55%.
- •Risk reduction for greater hand hygiene decreased as baseline compliance increased.
Background
Quantitative tools are needed to relate infection control interventions to infection
risk reductions.
Methods
A model for predicting virus concentrations on hands was used to predict rotavirus,
rhinovirus, and influenza A virus doses. Variability in behaviors, transfer efficiencies
for various contact types, and surface areas of contact were included. Dose-response
curves were used to relate estimated doses to infection risks. Percent reductions
from baseline in average rotavirus, rhinovirus, and influenza A virus dose and infection
risk were calculated for interventions.
Results
Baseline average infection risks for rotavirus, rhinovirus, and influenza A virus
were 0.43, 0.20, and 5.51 × 10−6, respectively. One and 2 cleaning events decreased average viral infection risks
by 6.98%-17.06% and 13.95%-34.66%, respectively. A 15% increase in hand compliance
decreased average infection risks by 6.98%-20.51%. A 15% increase in hand hygiene
compliance paired with 2 cleaning events decreased average infection risks by 20.93%-47.55%.
Discussion
This study demonstrates the infection risk benefits of combined interventions.
Conclusions
Models such as the one in this study could be used to optimize timing and frequency
of cleaning events and to create hand hygiene compliance goals to achieve infection
risk targets.
Key Words
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Article Info
Publication History
Published online: July 19, 2019
Footnotes
Conflicts of interest: None to report.
Identification
Copyright
© 2019 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
