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Particle control reduces fine and ultrafine particles greater than HEPA filtration in live operating rooms and kills biologic warfare surrogate

Published:January 05, 2020DOI:https://doi.org/10.1016/j.ajic.2019.11.017

      Highlights

      Particle control technology:
      • Reduced airborne particles by 95% compared to standard ventilation in operating rooms.
      • Killed 95% of Bacillus subtilis (anthrax surrogate) within three hours.
      • Could significantly reduce airborne infection in hospitals and healthcare settings.

      Background

      Controlling indoor air quality and the airborne transmission of infectious agents in hospitals is critical. The most hazardous particles and pathogens are not easily eliminated by traditionally passive air cleansing.

      Methods

      We studied the effect of a novel particle control technology on airborne particulate matter in 2 live real-world operating room settings and on pathogen survival in a microbiology laboratory.

      Results

      Particle control technology reduced operating room particle and pathogen loads by 94.4% in a community hospital operating room, and by 95% in an academic medical center operating room. The addition of particle control technology to a collector loaded with a biologic warfare surrogate resulted in a 95% kill rate of an anthrax surrogate (Bacillus subtilis) within 3 hours.

      Discussion

      Deployment of this emerging technology could significantly reduce indoor air contamination and associated infections in operating rooms, hospital isolation rooms, and intensive care settings, as well as reduce inflammatory responses to airborne particles.

      Conclusions

      The particle control technology studied may protect patients from hospital-acquired infections, reduce inflammatory pulmonary disease, and mitigate exposure to biologic weapons.

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      Linked Article

      • Erratum
        American Journal of Infection ControlVol. 48Issue 12
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          In the article “Particle Control Reduces Fine and Ultra-fine Particles Great Than HEPA Filtration in Live Operating Rooms and Kills Biologic Warfare Surrogate.” by Mark H. Ereth, et al. in the July issue of the American Journal of Infection Control (2020;48(7):777-80) the last paragraph of page 1 and the first full paragraph of page 2 were incorrect.
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