Efficacy of a multi-purpose high level disinfection cabinet against Candida auris and other health care-associated pathogen

Published:December 23, 2019DOI:


      • Portable equipment is a source for pathogen dissemination.
      • We tested a high-level disinfection cabinet for small devices.
      • The technology disperses droplets of peracetic acid and hydrogen peroxide.
      • The disinfection cabinet was effective against multiple organisms
      • Candida auris was eliminated from inoculated equipment
      Portable equipment and other small devices used in health care are a potential source for dissemination of pathogens. We demonstrated that a high-level disinfection cabinet using ultrasonic submicron droplets of peracetic acid and hydrogen peroxide was effective against methicillin-resistant Staphylococcus aureus, Clostridiodes difficile spores, the nonenveloped virus bacteriophage MS2, and Candida auris on steel disk carriers. The device also eliminated Candida auris inoculated on real-world items of portable equipment.

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        • Donskey CJ
        Beyond high-touch surfaces: portable equipment and floors as potential sources of transmission of health care-associated pathogens.
        Am J Infect Control. 2019; 47S: A90-A95
        • Eyre DW
        • Sheppard AE
        • Madder H
        • et al.
        A Candida auris outbreak and its control in an intensive care setting.
        N Engl J Med. 2018; 379: 1322-1331
        • Havill NL
        • Havill HL
        • Mangione E
        • Dumigan DG
        • Boyce JM
        Cleanliness of portable medical equipment disinfected by nursing staff.
        Am J Infect Control. 2011; 39: 602-604
        • Havill NL
        • Moore BA
        • Boyce JM
        Comparison of the microbiological efficacy of hydrogen peroxide vapor and ultraviolet light processes for room decontamination.
        Infect Control Hosp Epidemiol. 2012; 33: 507-512
        • Mana TSC
        • Sitzlar B
        • Cadnum JL
        • Jencson AL
        • Koganti S
        • Donskey CJ
        Evaluation of an automated room decontamination device using aerosolized peracetic acid.
        Am J Infect Control. 2017; 45: 327-329
      1. American Society for Testing and Materials International: Designation E2197-11: standard quantitative disk carrier test method for determining bactericidal, virucidal, fungicidal, mycobactericidal, and sporicidal activities of chemicals. West Conshohocken, PA: ASTM International; 2011:1-13.

      2. SOP: OECD quantitative method for evaluating the efficacy of liquid antimicrobials against Candida auris on hard, non-porous surfaces method ID: MB-35-00. Available at: Accessed December 18, 2019.

        • Cadnum JL
        • Shaikh AA
        • Piedrahita CT
        • et al.
        Relative resistance of the emerging fungal pathogen Candida auris and other Candida species to killing by ultraviolet light.
        Infect Control Hosp Epidemiol. 2018; 39: 94-96