Highlights
- •Adherence to blood culture bundle can reduce contamination rate.
- •Less contamination when collected from superficial veins of the cubital fossa.
- •Using chlorhexidine alcohol reduced contamination.
Abstract
Background
Inappropriate blood collection subjected to blood culture (BC) causes BC contamination
and may complicate the diagnose is of infectious diseases. Therefore, we developed
a bundle based on the guideline recommendations for appropriate blood collection and
examined the effects of bundle introduction.
Methods
We performed a retrospective analysis of BC samples to determine the contamination
rates before and after introducing the BC bundle. We also analyzed the correlation
between the compliance rate of the bundle and contamination rate, and between each
bundle element and contamination.
Results
After the introduction of the bundle, the contamination rate was significantly reduced
from 5.4% ± 0.9% to 1.7± 0.7% (P < .01). The compliance rate of the bundle was significantly associated with a lower
contamination rate (P < .01). Multivariable logistic regression showed that collection from superficial
veins of the cubital fossa (odds ratio [OR], 0.25; 95% confidence interval [CI], 0.13-0.51,
P < .01) and disinfection of the skin at the blood collection site with 1% chlorhexidine
alcohol swab (OR, 0.41; 95% CI, 0.25-0.68, P < .01) were significantly associated with lower contamination.
Conclusions
This study suggests that the introduction of the BC bundle significantly reduced the
contamination rate, and bundle compliance was associated with a lower contamination
rate.
Key Words
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Article Info
Publication History
Published online: December 01, 2021
Footnotes
Conflicts of interest: The authors declare that they have no conflicts of interest.
Author contributions: All authors met the ICMJE authorship criteria. Fumiko Kawanishi and Kyohei Yoshioka were responsible for the organization and coordination of the study. Kenta Minami and Tomoyuki Yamada developed the study design and held responsibility for the data analysis. Akira Ukimura and Taku Ogawa administered this project. All authors contributed to the writing of the final manuscript and to the management or administration of the study.
Identification
Copyright
© 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
