Highlights
- •Healthcare facility-onset Clostridioides difficile infection across an 11-hospital system rose after the spring of 2020.
- •The reason for the increase in C. difficile infections is multifactorial.
- •The increase in C. difficile during the spring of 2020 correlated with an increase in cephalosporin use.
Contrary to national reports, rates of healthcare facility-onset Clostridioides difficile infection across an 11-hospital system rose after the spring of 2020, when New York
City was the epicenter for the COVID-19 pandemic. Antibiotic pressure from an escalation
in cephalosporin usage correlated with this increase. The majority of cases of Clostridioides difficile were in patients without COVID-19, suggesting the pandemic has adversely impacted
the healthcare of other inpatients.
Key words
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Article info
Publication history
Published online: May 12, 2022
Footnotes
Conflicts of interest: None to report.
Identification
Copyright
Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc.
