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- •Extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening disease.
- •The bactericidal effect of far- ultraviolet C (far-UVC) on the ESBL-producing Escherichia coli (E. coli) was shown.
- •Irradiation with far- UVC may be effective in preventing infection by ESBL-producing E. coli.
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Subscribe to American Journal of Infection ControlReferences
Extended-Spectrum Beta-Lactamase (ESBL) Producing Enterobacteriaceae /Antimicrobial Resistance (AR/AMR). TRACK: 2019 Antibiotic Resistance Threats Report. Accessed December 23, 2021. https://www.cdc.gov/drugresistance/pdf/threats-report/esbl-508.pdf
- Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern.Lancet Infect Dis. 2008; 8: 159-166
- Germicidal efficacy and mammalian skin safety of 222-nm UV light.Radiat Res. 2017; 187: 483-491
- 222-nm UVC inactivates a wide spectrum of microbial pathogens.J Hosp Infect. 2020; S0195-6701 (20) 30129-8
- Evaluation of acute corneal damage induced by 222-nm and 254-nm ultraviolet light in Sprague-Dawley rats.Free Radic Res. 2019; 53: 611-617
- Effectiveness of 222-nm ultraviolet light on disinfecting SARS-CoV-2 surface contamination.Am J Infect Control. 2021; 49: 299-301
- Pilot study on the decontamination efficacy of an installed 222-nm ultraviolet disinfection device (Care222™), with a motion sensor, in a shared bathroom.Photodiagnosis Photodyn Ther. 2021; 34102334
- Inactivation of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli by UVA-LED irradiation system.J Med Invest. 2020; 67: 163-169
- DNA damage kills bacterial spores and cells exposed to 222-nanometer UV radiation.Appl Environ Microbiol. 2020; 86 (e03039-19)
- The synergistic bactericidal mechanism of simultaneous treatment with a 222-nanometer krypton-chlorine Excilamp and a 254-nanometer low-pressure mercury lamp.Appl Environ Microbiol. 2018; 85 (e01952-18)
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Footnotes
Conflict of interest: None of the authors declare any financial or non-financial conflict of Interest.
Author contributions: J.N.: Idea, Concept, Writing. S.F., Y.K., Y.O., T.F., N.K., K.O., H.T., S.H.: Investigation, Y.S., T.Y., T.T.: Analyses, Writing.