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The bactericidal effect of far-UVC on ESBL-producing Escherichia coli

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      • Extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening disease.
      • The bactericidal effect of far- ultraviolet C (far-UVC) on the ESBL-producing Escherichia coli (E. coli) was shown.
      • Irradiation with far- UVC may be effective in preventing infection by ESBL-producing E. coli.
      Because extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening disease and effective treatments need to be developed, we examined the bactericidal effect of far-ultraviolet C (far-UVC) light therapy on ESBL-producing Escherichia coli (E. coli). The bactericidal effect on 2 types of ESBL-producing E. coli was the same as that on the wild strain although the results of drug resistance tests varied among these strains. We believe that irradiation with far-UVC is effective in preventing infection by ESBL-producing E. coli in health care settings.

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      References

      1. Extended-Spectrum Beta-Lactamase (ESBL) Producing Enterobacteriaceae /Antimicrobial Resistance (AR/AMR). TRACK: 2019 Antibiotic Resistance Threats Report. https://www.cdc.gov/drugresistance/pdf/threats-report/esbl-508.pdf. Assessed December 23, 2021.

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