Highlight
- •Extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening disease.
- •The bactericidal effect of far- ultraviolet C (far-UVC) on the ESBL-producing Escherichia coli (E. coli) was shown.
- •Irradiation with far- UVC may be effective in preventing infection by ESBL-producing E. coli.
Because extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening
disease and effective treatments need to be developed, we examined the bactericidal
effect of far-ultraviolet C (far-UVC) light therapy on ESBL-producing Escherichia coli (E. coli). The bactericidal effect on 2 types of ESBL-producing E. coli was the same as that on the wild strain although the results of drug resistance tests
varied among these strains. We believe that irradiation with far-UVC is effective
in preventing infection by ESBL-producing E. coli in health care settings.
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References
Extended-Spectrum Beta-Lactamase (ESBL) Producing Enterobacteriaceae /Antimicrobial Resistance (AR/AMR). TRACK: 2019 Antibiotic Resistance Threats Report. Accessed December 23, 2021. https://www.cdc.gov/drugresistance/pdf/threats-report/esbl-508.pdf
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- Inactivation of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli by UVA-LED irradiation system.J Med Invest. 2020; 67: 163-169
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Article Info
Publication History
Published online: May 12, 2022
Footnotes
Conflict of interest: None of the authors declare any financial or non-financial conflict of Interest.
Author contributions: J.N.: Idea, Concept, Writing. S.F., Y.K., Y.O., T.F., N.K., K.O., H.T., S.H.: Investigation, Y.S., T.Y., T.T.: Analyses, Writing.
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© 2022 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
