- •Having a hematological malignancy is a risk factor for CRI.
- •Whether neutropenia at the moment of catheter placement is a risk factor for CLABSI is uncertain.
- •Among long-term catheters, tunneled, lumen diameter ≥ 7Fr, and multi-lumen devices presented the higher incidence of infections.
- •Ports showed lower rates of CLABSI.
- •Gram-positive bacteria are the most frequent pathogens.
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- Antimicrobial-resistant pathogens associated with healthcare-associated infections summary of data reported to the National Health Care Safety Network at the Centers for Disease Control and Prevention, 2009–2010.Infect Control Hosp Epidemiol. 2013; 34: 1-14https://doi.org/10.1086/668770
- Catheter-related infections in pediatric patients with cancer.Eur J Clin Microbiol Infect Dis. 2012; 31: 2869-2877https://doi.org/10.1007/s10096-012-1652-4
- Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America.Clin Infect Dis. 2011; 52: e56-e93https://doi.org/10.1093/cid/cir073
- Central venous catheter–related infections in hematology and oncology: 2020 updated guidelines on diagnosis, management, and prevention by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO).Ann Hematol. 2021; 100: 239-259https://doi.org/10.1007/s00277-020-04286-x
- The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.BMJ. 2021; 372: n71https://doi.org/10.1136/bmj.n71
The Cochrane Collaboration 2020. RevMan 5.4.1. Published online 2020.
- The heterogeneity statistic I2 can be biased in small meta-analyses.BMC Med Res Methodol. 2015; 15: 35https://doi.org/10.1186/s12874-015-0024-z
Wells GA, Shea B, O'Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analysis. Published 2011. Available at: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp
- Closing the quality gap: revisiting the state of the science.in: (US) A for HR and Q Vol. 3: Quality Improvement Interventions To Address Health Disparities. Evidence R, 2012 (Available at:)
- Severe neutropenia at time of port insertion is not a risk factor for catheter-associated infections in children with acute lymphoblastic leukemia.Cancer. 2010; 116: 4368-4375https://doi.org/10.1002/cncr.25286
- Complications and risk factors of infection in pediatric hemato-oncology patients with totally implantable access ports (TIAPs).Pediatr Blood Cancer. 2010; 54: 546-551https://doi.org/10.1002/pbc.22286
- Neutropenia at the time of subcutaneous port insertion may not be a risk factor for early infectious complications in pediatric oncology patients.J Pediatr Surg. 2019; 54: 145-149https://doi.org/10.1016/j.jpedsurg.2018.10.024
- Severe neutropenia at the time of implantable subcutaneous chest port insertion is not a risk factor for port removal at a tertiary pediatric center.J Vasc Interv Radiol. 2017; 28: 398-402https://doi.org/10.1016/j.jvir.2016.10.007
- Risk factors for central line-associated bloodstream infection in pediatric oncology patients with a totally implantable venous access port: a cohort study.Pediatr Blood Cancer. 2017; 64: 336-342https://doi.org/10.1002/pbc.26225
- Characteristic of catheters and of children with oncohematological disease *.Cogitare enferm. 2017; 22: 1-10
- Factors affecting the timing of a central line associated bloodstream infection onset in children with cancer.J Pediatr Oncol Nurs. 2021; 38: 26-35https://doi.org/10.1177/1043454220966831
- Central venous catheters and bloodstream infection during induction therapy in children with acute lymphoblastic Leukemia.J Pediatr Hematol Oncol. 2016; 38: e82-e87https://doi.org/10.1097/MPH.0000000000000519
- Placing of tunneled central venous catheters prior to induction chemotherapy in children with acute lymphoblastic leukemia.Pediatr Blood Cancer. 2010; 55: 309-313https://doi.org/10.1002/pbc.22530
- Risk factors for bacteremia and central line–associated blood stream infections in children with acute myelogenous leukemia: a single-institution report.Pediatr Blood Cancer. 2017; 64: 1-7https://doi.org/10.1002/pbc.26254
- Central line associated blood stream infections in pediatric hematology/oncology patients with different types of central lines.Pediatr Blood Cancer. 2016; 63: 1603-1607https://doi.org/10.1002/pbc.26053
- Microbiology and risk factors for central line-associated bloodstream infections among pediatric oncology outpatients: a single institution experience of 41 cases.J Pediatr Hematol Oncol. 2013; 35: 71-76https://doi.org/10.1097/MPH.0b013e3182820edd
- Incidence, severity and outcome of central line related complications in pediatric oncology patients; a single center study.J Pediatr Surg. 2019; 54: 1894-1900https://doi.org/10.1016/j.jpedsurg.2018.10.054
- Patient and central venous catheter related risk factors for blood stream infections in children receiving chemotherapy.Pediatr Blood Cancer. 2015; 62: 471-476https://doi.org/10.1002/pbc.25281
Evidence-Based Care Bundles. Institute for Healthcare Improvement. Published 2012. Accessed June 15, 2022. http://www.ihi.org/resources/Pages/Tools/HowtoGuidePreventCentralLineAssociatedBloodstreamInfection.aspx
- Prospective surveillance study of blood stream infections associated with central venous access devices (port-type) in children with acute leukemia.J Pediatr Hematol Oncol. 2013; 35: e194-e199https://doi.org/10.1097/MPH.0b013e318290c24f
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Declaration of interests: The authors declare no conflict of interest.