Highlights
- •Methicillin-Resistant Staphylococcus aureus (MRSA) causes a fatal and invasive form of the disease.
- •Healthcare Workers (HCWs) are at greater risk of colonization with MRSA.
- •HCWs cause transmission of MRSA within a hospital setting.
- •Prevalence of MRSA carriage among HCWs is slightly higher in South Asia than in European and American Nation.
- •Our study summarized the overall MRSA carriage rate of 9.23% (95%CI; 6.50%, 12.35%) among HCWs in SAARC nations, with nurses having higher odds of getting infected.
Background
This study aimed to estimate the pooled prevalence and sub–group-specific prevalence
of Methicillin-resistant Staphylococcus aureus (MRSA) carrier rate among Healthcare Workers (HCWs) in South Asia.
Methodology
We considered prospective and cross-sectional studies published in the English language
with participants ≥50 by searching different electronic databases to locate the relevant
articles that reported the epidemiology of MRSA. The participants were healthy South
Asian nationality HCWs (asymptomatic for any infectious disease) of any age and gender
with a definitive diagnosis of MRSA carriage. The result was synthesized for the pooled
prevalence of MRSA carriers among HCWs using 95% confidence interval (CI) with DerSimonian
and Laird random-effects models.
Results
The pooled prevalence of MRSA carriage among HCWs was 9.23% (95%CI; 6.50%, 12.35%)
with a range from 0.67% to 36.06%. The prevalence in India, Nepal, Pakistan, Sri Lanka,
and Bangladesh was 5.65% (95%CI; 3.65%, 8.03%), 8.83% (95%CI; 6.77%, 11.11%), 17.20%
(95%CI; 10.70%, 24.85%), 22.56% (95%CI; 4.93%, 47.83%), and 4.93% (95%CI; 1.88%, 9.20%)
respectively. The pooled prevalence of MRSA carriage among nurses and doctors was
8.90% (95%CI; 6.00%, 12.24%) and 6.53% (95%CI; 3.63%, 10.06%) respectively.
Conclusion
The findings from our study suggests that if the propagation of MRSA continues, then
it can lead to a situation of an outbreak. Hence, proper preventive measures are to
be adopted to prevent this outbreak.
Graphical Abstract
Graphical Abstract
Key Words
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Published online: June 09, 2022
Footnotes
Conflicts of interest: The authors have declared that no competing interests exist. The authors have no support or funding to report.
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© 2022 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
