Abstract
Introduction
Measles is one of the most contagious of all infectious diseases, for example, up
to nine out of ten susceptible people with close contact to a measles patient will
develop measles. In countries where measles is rare, transmissions in healthcare facilities
have been a key factor in amplifying outbreaks
Objectives
describe the hospital transmission of measles among unvaccinated children in pediatric
service, challenges faced and recommendations for healthcare settings by applying
the Swiss cheese model.
Method
Between December, 9th 2019 and January 24th 2020, multiple exposures to measles cases
occurred. The incident and factors that led to the outbreak are described. The MF-NCR
sequence analysis was also conducted on the three strains isolated from the cases.
Results
The outbreak extended from December 9th 2019 to January 24th 2019, which resulted in 110 exposed individuals (85 HCWs and 25 patients). Eleven
(44%) children exposed were vaccinated, 14 (56%) were not yet vaccinated and the measles
status of 10 (11.8%) HCWs was not known at the time of the outbreak. Two infants acquired
measles in the hospital, and both required ICU care. Three infants and one HCW received
immunoglobulin. The phylogenetic tree of the MF-NCR sequencing confirmed that all
three cases had 100% identical Measles strain.
Conclusion
In countries where measles elimination goals are achieved, a multifaceted approach
to prevent measles transmission in healthcare is vital to maintain patient safety.
Keywords
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