Abstract
Background: Hand transmission of microbes by health care workers is a primary cause of nosocomial
infections in both long-term and acute care facilities. Compliance with effective
handwashing and hand sanitization regimens can break this cycle. Methods: We investigated the antimicrobial efficacy and irritation potential of 5 handwash
product regimens: a nonantimicrobial lotion soap, an antimicrobial lotion soap, an
alcohol gel sanitizer, a nonantimicrobial lotion soap with an alcohol gel sanitizer,
and an antimicrobial lotion soap with an alcohol gel sanitizer. The regimens were
evaluated by using a Healthcare Personnel Handwash procedure, and irritation was assessed
by using expert hand evaluation after 25 consecutive washes. Results: The Healthcare Personnel Handwash data showed that the mean log reductions from baseline
were greatest for the lotion soaps with alcohol gel sanitizer, less for the alcohol
and the antimicrobial soap alone, and least for the bland soap. All of the product
regimens showed a low potential for skin irritation. Conclusion: In terms of both microorganism reduction and skin irritation, the most effective
product regimens were the use of alcohol gel sanitizer in combination with either
an antimicrobial or a plain lotion soap. (AJIC Am J Infect Control 1999;27:332-8)
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References
- A causal link between handwashing and risk of infection?.Infect Control Hosp Epidemiol. 1988; 9: 28-36
- Handwashing: a ritual revisited.in: Chemical germicides in health care. Association for Professionals Infection Control and Epidemiology, Washington (DC)1995: 163-178 (211-9)
- Epidemiology of nosocomial infections.in: Infectious diseases. : WB Saunders Co, Philadelphia1992: 96-106
- The epidemiology and prevention of nosocomial infections.in: Disinfection, sterilization, and preservation. : Lea & Fegier, Philadelphia1991: 663-675
- Understanding the cost of nosocomial infections.in: Prevention and control of nosocomial infections. : Williams & Wilkins, Baltimore1993: 21-41
- The global impact of infection control.in: Prevention and control of nosocomial infections. : Williams & Wilkins, Baltimore1993: 13-20
- Comparative efficacy of alternative hand-washing agents in reducing nosocomial infections in intensive care units.N Engl J Med. 1992; 327: 88-93
- Hand-washing and nosocomial infections.N Engl J Med. 1992; 327: 120-122
- A broad-based approach to evaluating topical antimicrobial products.in: Handbook of disinfectants and antiseptics. : Marcel-Dekker, New York1996: 17-33
21 CFR Sect 333.470 (1994).
- Evaluation of three handwash modalities commonly employed in the food industry.Dairy Food Environ Sanitation. 1992; 12: 615-618
- Evaluation of three microorganism recovery procedures used to determine handwash efficacy.Dairy Food Environ Sanitation. 1993; 13: 520-523
- Comparative investigation on recovering bacteria from artificially contaminated hands.Zentralbl Bakteriol [Orig B]. 1975; 160: 412-431
- Influence of some variables on the results of evaluations of procedures for hygienic hand disinfection.Hyg Med. 1982; 7: 157-166
- APIC guideline for handwashing and hand antisepsis in health care settings.AJIC Am J Infect Control. 1995; 23: 251-269
- Introduction to statistical analysis.in: 4th ed. : McGraw-Hill, New York1983: 131-133
- Selecting and ordering populations.in: : John Wiley, New York1977: 14-57
- Applications, basics and computing of exploratory data analysis.in: : Duxbury, Boston1981: 3-121
- Alcohols.in: Disinfection, sterilization, and preservation. : Lea & Febiger, Philadelphia1991: 191-203
- Intermittent use of an antimicrobial hand gel for reducing soap irritation of health care personnel.in: AJIC Am J Infect Control. 18. 1990: 194-200
Health Care Personnel Handwash Procedure, 21 CFR Part 333.470 (1994).
Article Info
Footnotes
☆From the BioScience Laboratories, Inc, Bozeman,a and GOJO Industries, Inc, Cuyahoga Falls.b
☆☆Supported in part by GOJO Industries, Inc.
★Reprint requests: Eleanor J. Fendler, PhD, GOJO Industries, Inc, 3783 State Road, Cuyahoga Falls, OH 44223.
★★17/46/96194
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Copyright
© 1999 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.